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BSI BS EN 16418:2014

Paper and board. Determination of the cytotoxicity of aqueous extracts using a metabolically competent hepatoma cell line (HepG2)
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BSI BS EN 16418:2014

Paper and board. Determination of the cytotoxicity of aqueous extracts using a metabolically competent hepatoma cell line (HepG2)

PUBLISH DATE 2014
PAGES 24
BSI BS EN 16418:2014

This European Standard specifies a test method for the laboratory assessment of the potential cytotoxic effect of paper and board intended to come into contact with foodstuffs using specifically the HepG2 cell line.

Compared to the EN 15845[1], HepG2 cells are more representative of a human oral exposure to xenobiotics, due to the presence in the cells of phase I, II and III enzymes of the metabolism.

SDO BSI: British Standards Institution
Document Number EN 16418
Publication Date April 30, 2014
Language en - English
Page Count 24
Revision Level
Supercedes
Committee PAI/11
Publish Date Document Id Type View
April 30, 2014 BS EN 16418:2014 Revision