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Current Consolidated

BSI BS EN ISO 21243:2025

Radiation protection. Performance criteria for laboratories performing initial cytogenetic dose assessment of mass casualties in radiological or nuclear emergencies. General principles and application to dicentric assay
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The purpose of this document is to give an overview of the minimum requirements for performing the dicentric assay with quality control measures using mitogen stimulated peripheral blood lymphocytes for initial assessment of individuals involved in a mass casualty scenario. The dicentric assay is the use of chromosome damage to quickly estimate approximate radiation doses received by individuals in order to supplement the early clinical categorization of casualties. This document focuses on the organizational and operational aspects of applying the dicentric assay in an initial assessment mode. The technical aspects of the dicentric assay can be found in ISO 19238. This document is applicable either to an experienced biological dosimetry laboratory working alone or to a network of collaborating laboratories (as defined in Clause 7).
SDO BSI: British Standards Institution
Document Number ISO 21243
Publication Date Sept. 30, 2025
Language en - English
Page Count 28
Revision Level
Supercedes
Committee NCE/2
Publish Date Document Id Type View
Nov. 24, 2022 BS ISO 21243:2022 Revision
Sept. 30, 2008 BS ISO 21243:2008 Revision
Sept. 30, 2025 BS EN ISO 21243:2025 Consolidated