ISO/TS 22304:2008

Current Revision
Tobacco - Determination of tobacco specific nitrosamines - Method using alkaline dichloromethane extraction

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Tobacco - Determination of tobacco specific nitrosamines - Method using alkaline dichloromethane extraction

PUBLISH DATE 2008

ISO/TS 22304:2008 specifies the procedure for the determination of the tobacco specific nitrosamines (TSNAs):

  • N-nitrosonornicotine (NNN),
  • N-nitrosoanatabine (NAT),
  • N-nitrosoanabasine (NAB), and
  • 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

These compounds are determined in ground leaf tobacco, manufactured tobacco, and tobacco products.

The determination is by means of gas chromatography.

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