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Determination of particle size distribution - Single particle light interaction methods - Part 3: Light extinction liquid-borne particle counter
This document describes a **calibration and verification method** for a light extinction liquid-borne particle counter (LELPC), which is used to measure the size and particle number concentration of particles suspended in liquid. The light extinction method described in this document is based on *single particle measurements*. The typical size range of particles measured by this method is between 1 µm and 100 µm in particle size.
The method is applicable to instruments used for the evaluation of the cleanliness of pharmaceutical products (e.g. injections, water for injections, infusions), as well as the measurement of number and size distribution of particles in various liquids.
The following are within the scope of this document:
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