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ISO 21766:2021

Tobacco and tobacco products - Determination of tobacco-specific nitrosamines in tobacco products - Method using LC-MS/MS
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ISO 21766:2021

Tobacco and tobacco products - Determination of tobacco-specific nitrosamines in tobacco products - Method using LC-MS/MS

PUBLISH DATE 2021
ISO 21766:2021

This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in tobacco and the following tobacco products: cigarettes, cigars and smokeless tobacco products using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS).

The TSNAs determined with this method are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

SDO ISO: International Organization for Standardization
Document Number ISO 21766
Publication Date Feb. 1, 2021
Language en - English
Page Count
Revision Level
Supercedes
Committee ISO/TC 126
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